Why You’ll Love This Recipe

I love this recipe because it’s pure comfort made simple. With just a few pantry staples and a can of biscuit dough, it comes together in minutes. The combination of chicken, ranch seasoning, cheese, and creamy sauce gives it that homestyle flavor that reminds me of classic Southern casseroles. It’s hearty enough to serve on its own but also pairs beautifully with a simple salad or roasted veggies.

Ingredients

(Note: All ingredient amounts are listed in the recipe card below.)

3 cups cooked chicken, shredded or chopped
2 (10.5 oz) cans condensed cream of chicken soup
1 1/2 cups sour cream
2 cups shredded cheddar cheese, divided
2 tablespoons dry ranch dressing mix
1/4 cup finely diced red bell pepper
1 (12 oz) can refrigerated biscuit dough, quartered (Grands Jr)

Directions

1. I preheat the oven to 350°F (175°C) and lightly grease a 9×13-inch baking dish.

2. In a large bowl, I mix together the cooked chicken, cream of chicken soup, sour cream, 1 cup of cheddar cheese, ranch dressing mix, and diced red bell pepper until everything is well combined.

3. I gently fold in the quartered biscuit dough pieces, making sure they’re evenly coated in the creamy mixture.

4. I transfer the mixture to the prepared baking dish, spreading it evenly with a spatula.

5. I sprinkle the remaining 1 cup of shredded cheddar cheese over the top.

6. I bake the casserole uncovered for 30–35 minutes, or until it’s hot, bubbly, and the biscuits are golden brown.

7. I let it cool for about 5 minutes before serving to allow the sauce to set slightly.

Servings and Timing

This recipe makes about 6–8 servings and takes around 45 minutes total—10 minutes for prep and 35 minutes for baking.

Variations

I sometimes add vegetables like peas, corn, or broccoli for extra nutrition and color. For a spicy version, I stir in diced jalapeños or a dash of hot sauce. If I want to change up the flavor, I use cream of mushroom soup instead of chicken or swap the cheddar for mozzarella or pepper jack cheese. I’ve also tried using leftover turkey instead of chicken—it’s just as delicious.

Storage/Reheating

I store leftovers in an airtight container in the refrigerator for up to 4 days. To reheat, I bake them in the oven at 350°F (175°C) for about 15 minutes or microwave individual portions for 1–2 minutes. This casserole also freezes well—I freeze cooled portions in airtight containers for up to 2 months and thaw them in the fridge before reheating.

FAQs

Can I use homemade biscuits instead of canned?

Yes, I use half a batch of homemade biscuit dough—it works beautifully.

Can I make this ahead of time?

Yes, I assemble the casserole up to a day in advance, cover it, and refrigerate it. I bake it when ready to serve.

What kind of chicken works best?

I use rotisserie chicken for convenience, but canned or leftover cooked chicken works just as well.

Can I use a different soup base?

Yes, cream of mushroom or cream of celery soup both add great flavor.

Can I add vegetables?

Definitely! I love adding peas, corn, green beans, or chopped broccoli for a pop of color and nutrients.

How do I keep the biscuits from getting soggy?

I make sure the mixture isn’t too wet and bake until the biscuits are golden and crisp on top.

Can I make this in smaller portions?

Yes, I divide the mixture into smaller baking dishes or ramekins for individual servings.

Can I use Greek yogurt instead of sour cream?

Yes, I sometimes use plain Greek yogurt for a lighter version—it still stays creamy and delicious.

What should I serve with it?

I like pairing it with a green salad, roasted vegetables, or even coleslaw to balance the richness.

Can I make it vegetarian?

Yes, I replace the chicken with sautéed mushrooms, spinach, or mixed vegetables and use cream of mushroom soup.

Conclusion

This Chicken Bubble Biscuit Bake Casserole is the definition of comfort food done right. I love how quick and easy it is to make, yet it tastes like something you’d find at a cozy family diner. The creamy sauce, melted cheese, savory chicken, and buttery biscuits come together perfectly in every bite. It’s warm, hearty, and sure to become a family favorite for weeknights, potlucks, or whenever I want a comforting meal straight from the oven.